ENTRY       D00109                      Drug
NAME        Aspirin (JP15/USP);
            Acetylsalicylic acid;
            Easprin (TN)
FORMULA     C9H8O4
MASS        180.0423
TARGET      cyclooxygenase-1 (COX-1) inhibitor [HSA:5742] [EC:1.14.99.1];
            cyclooxygenase-2 (COX-2) inhibitor [HSA:5743] [EC:1.14.99.1]
ACTIVITY    Analgesic;
            Antipyretic;
            Antirheumatic
REMARK      Same as: C01405
            Therapeutic category: 1143 3399
            ATC code: A01AD05 B01AC06 N02BA01
COMMENT     Name previously used: Acetylsalicylic acid
            Component of Bufferin (TN), Percodan (TN), Darvon compound-65 (TN),
            E.A.C (TN)
PATHWAY     PATH: map07110  Benzoic acid family
            PATH: map07219  Cyclooxygenase inhibitors
DBLINKS     CAS: 50-78-2
            PubChem: 7847177
            ChEBI: 15365
            DrugBank: DB00945
            PDB-CCD: AIN
            DailyMed: aspirin
            LigandBox: D00109
ATOM        13
            1   C8y C    20.2981  -15.8105
            2   C8y C    21.5226  -16.5029
            3   C8x C    19.0928  -16.5029
            4   C6a C    20.2981  -14.6227
            5   C8x C    21.5226  -17.9133
            6   O7a O    22.7278  -15.8040
            7   C8x C    19.0928  -17.9133
            8   O6a O    21.5033  -13.9240
            9   O6a O    19.0863  -13.9304
            10  C8x C    20.2981  -18.6250
            11  C7a C    23.9396  -16.4964
            12  C1a C    25.1450  -15.7977
            13  O7a O    23.9396  -17.8942
BOND        13
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11   11  12 1
            12   11  13 2
            13    7  10 2
///